When deploying Office 365 Click-to-Run then I want to remove as many as possible popup for the end users – there for this guide.

First download the “Office 2016 Administrative Template files (ADMX/ADML) and Office Customization Tool” from Microsoft : https://www.microsoft.com/en-us/download/details.aspx?id=49030

Update your GPO Central Store with the downloaded ADMX/ADML files.

First thing that the user see is this

This can be removed by this GPO

User Configuration -> Policies -> Administrative Templates -> Microsoft Office 2016 -> First Run

Then the user get this

This can be removed by this GPO

User Configuration -> Policies -> Administrative Templates -> Microsoft Office 2016 -> Subscription Activation

Then the user get this

This can be removed this GPO

User Configuration -> Policies -> Administrative Templates -> Microsoft Office 2016 -> Privacy -> Trust Center

Then the user get this

User Configuration -> Preferences -> Windows Settings -> Registry

HKEY_CURRENT_USER Key path         SoftwareMicrosoftOffice16.0Registration Value name    AcceptAllEulas Value type       REG_DWORD

Value data      1

And at last we in the EU get this

 User Configuration -> Preferences -> Windows Settings -> Registry

HKEY_CURRENT_USER Key path         SoftwareMicrosoftOffice16.0CommonGeneral Value name   ShownFileFmtPrompt Value type       REG_DWORD

Value data      1

And now all you have to do is deploy you new GPO the Office 2016 users.